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Prenatal fatty acid exposure not tied to childhood wheezing

Last Updated: 2004-09-29 14:42:53 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Levels of n-6 and n-3 fatty acids in the diets of pregnant women do not appear to have any important influence on the development of wheezing and allergies in their children, UK researchers report in the Journal of Allergy and Clinical Immunology.

It has been proposed that changing patterns of fatty acids in the diet may contribute to the growing rate of asthma and allergy in children, Dr. Seif O. Shaheen of King's College, London and colleagues note.

To investigate whether prenatal interaction of n-3 and N-6 fatty acids could be involved in an imbalance that ultimately might lead to the airway inflammation involved in asthma, the researchers studied thousands of blood samples obtained from women during late in pregnancy, as well as umbilical cord blood samples.

Initially it appeared that there was a positive association between n-6 related fatty acids and wheezing, and a negative association between n-3 associated products and wheezing. But after the data were adjusted to correct for other risk factors, there were no significant differences.

This was also the case for relationships that appeared to be associated with eczema.

Thus the researchers conclude that they have "not found convincing evidence that higher exposure to n-6 versus n-3 fatty acids in utero promotes the development of eczema or wheezing in early childhood."

SOURCE: Journal of Allergy and Clinical Immunology, September 2004.

Copyright © 2004 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 

WHO bid to reduce maternal deaths

 

Pregnant women should have access to birth attendants, says the WHO

At least one woman dies during childbirth every minute in the developing world, health experts warn.

The World Health Organization is spearheading a campaign to reduce the numbers of women who die in this way.

It is calling for action to be taken to reduce the death toll of half a million women a year.

The WHO says women should have skilled birth attendants. It also wants better mortality data to improve knowledge of how many women die this way.

Women should not die giving birth

Joy Phumaphi, World Health Organization

The WHO estimates that maternal deaths are under-reported by as much as 50% . In 62 countries, there is no data on maternal mortality.

The causes of death include haemorrhage, infection, obstructed labour and unsafe abortion.

But it says the underlying reason for women dying in childbirth is unavailable, inaccessible, or poor quality healthcare.

The WHO says around a million children are left motherless each year. These children are 10 times more likely to die in childhood than children whose mothers have not died.

It estimates the risk of dying in pregnancy in the world's poorest countries is over a hundred times higher than in the richest ones.

'Deaths are preventable'

The Millennium Development Goals which include a target to reduce maternal mortality by three quarters by 2015.

The WHO is launching a campaign to train health workers in high-risk countries.

It has produced a manual explaining why women die from complications related to childbirth, and sets out how this can be avoided by using effective and affordable.

The WHO says an extra US$10m is needed to train decision-makers, national health planners and medical service providers in these countries.

Joy Phumaphi, WHO Assistant Director-General on Family and Community Health told a meeting of health experts in Nairobi: "Pregnancy is a normal, life-affirming state. Women should not die giving birth.

"Their deaths are preventable, even in the poorest countries. But it takes local knowledge, strength and partnership to ensure women's lives are saved."

She added: "One key task of the global health community is to close the gap in services for women in rich areas, and those in poor ones.

"If dead women are not even counted, then it seems they do not count. We have an invisible epidemic."

 

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