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Suicide Risk May Trace Back to Womb

 

September 23, 2004 08:48:47 PM PDT , HealthDay

 

By Serena Gordon
HealthDay Reporter

 

THURSDAY, Sep. 23 (HealthDayNews) -- While it may seem strange, what happened to you in the womb may affect your suicide risk later in life.

That's the conclusion of a study in the Sept. 25 issue of The Lancet that found if you were born to a teenage mother or had a low birth weight, the odds are higher that you might commit suicide as a teenager or young adult.

"I believe that it is an interaction between prenatal, genetic, and environmental conditions in which children were born and raised in [that contributed to the increased risk of suicide]," said the study's author, Dr. Danuta Wasserman, head of the Swedish National Center for Suicide Research and Prevention of Mental Ill-Health in Stockholm.

"Teenage motherhood is very stressful, and can be associated with poor diet, abuse, and also psychiatric disorders and psychological disturbances. These poor psychosocial conditions can influence gene expression that regulate effects like aggressivity, impulsivity and anxiety in vulnerable individuals."

Dr. Maria Oquendo, a clinical professor of psychiatry at Columbia University, who authored an editorial that accompanies the study in the same issue of the journal, had a reassuring message for parents. "Just because your baby is low-weight or you were young when they were born doesn't mean that they're at high risk for suicide." She said the study only found an association between those factors and suicide, not a direct cause-and-effect relationship.

Each year, almost 30,000 people in the United States commit suicide, according to the Substance Abuse and Mental Health Services Administration (SAMHSA). For each successful suicide, between eight and 25 people attempt suicide. It is the third leading cause of death in 15-to-24 year-olds, according to SAMHSA.

For this study, researchers gathered data from the Swedish birth register for all children born between 1973 and 1980. They found complete records on 713,370 youngsters.

As of Dec. 31, 1999, 563 of those children had committed suicide, and another 6,676 had attempted suicide.

The average suicide rate in Sweden is about 20 per 100,000 people, according to the researchers. Children born to teenage mothers and children who weighed less than 2 kilograms (about 4.5 pounds) at birth had more than double that risk.

Factors that increased the risk of suicide and attempted suicide included birth length (less than 47 centimeters), less than 12 years of maternal education, and being fourth or later in the family's birth order. A maternal age of more than 29 years appeared to be somewhat protective, lowering the risk of attempted suicide by 15 percent.

The researchers didn't look at the impact fathers might have on their offspring's risk of suicide.

Wasserman said the results of this study mean that "we need to monitor and support young mothers during their pregnancy and follow up those newborn children who are at risk with psychosocial and educational measures about diet, misuse of drugs, and coping skills, and to help with emotional and practical support when needed. Doctors, nurses, social workers, counselors, etc., need to be alerted that prevention needs to start before a child is born."

Oquendo agreed, and added that this study highlights "the importance of maternal nutrition and the need for improved healthcare for pregnant mothers."

More information

To learn more about the warning signs of suicide and what you can do to help someone contemplating suicide, visit the American Association of Suicidology.

 

End-of-life care for breast cancer may be inadequate

Last Updated: 2004-09-23 13:48:05 -0400 (Reuters Health)

By Megan Rauscher

NEW YORK (Reuters Health) - While supportive care to relieve symptoms is now the standard of care at the end of life, a new study shows that a "sizeable proportion" of breast cancer patients nearing death do not have access to such treatment, also referred to as palliative care.

"Palliative care has been shown to improve quality of life of dying patients with cancer," Dr. Bruno Gagnon from Royal Victoria Hospital in Montreal told Reuters Health. "Unfortunately, this study demonstrates that women dying of breast cancer had limited access to such care, especially the younger ones. "

Gagnon and colleagues analyzed the pattern of care at the end of life for 2,291 women terminally ill with breast cancer and found that the majority (75 percent) did not receive palliative care during the last six months of life.

"Very few" (6.9 percent) died at home, Gagnon said. More than two thirds (69.6 percent) died in acute care hospital beds.

This low rate of home deaths is "striking," the investigators report in the Journal of Clinical Oncology, and may be explained by the high level of accessibility to hospital beds in Quebec province, the site of the study.

Age was a factor in the receipt of palliative care. Women younger than age 50 were less likely to receive palliative care at the end of life than were women in middle age, while women older than 70 were the most likely to receive palliative care.

Commenting on these findings, Gagnon said: "The prevention of suffering is an integrated part of cancer control. Health care policies for end-of-life care should seriously promote health services for the terminally ill in view of preventing undue suffering."

SOURCE: Journal of Clinical Oncology, September 1, 2004.

Copyright © 2004 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 

Oral Antibiotic Treats Childhood Pneumonia in Developing Countries

 

September 24, 2004 06:03:17 AM PDT , HealthDay

 

FRIDAY, Sept. 24 (HealthDayNews) -- The oral antibiotic amoxicillin may offer an alternative to injectable penicillin for treating pneumonia in young children in developing countries.

That news is reported in an international study in this week's issue of The Lancet.

This could lead to better outcomes for those children and reduced health-care costs, the researchers say.

The study included about 1,700 children, aged 3 months to 5 years, with pneumonia in Africa, Asia and South America. They were randomly assigned to receive either oral amoxicillin or injectable penicillin.

Treatment failure after 48 hours -- the main measure of the study -- was the same in both groups (19 percent). The two groups also had no difference in outcome after five and 14 days.

"Our findings have several important beneficial implications if applied as public health policy; oral amoxicillin will reduce (1) the risk of needle-associated complications such as needle-borne infections; (2) the need for referral or admission; (3) treatment administration costs; and (4) transport, food and lost income costs for the family," researcher Shamin Qazi, of the World Health Organization, said in a prepared statement.

Each year, pneumonia and other respiratory diseases kill about 2 million children under age 5 in developing countries. Currently, injectable penicillin is the recommended treatment for severe pneumonia in these children, the study said.

More information

The American Lung Association has more about pneumonia.

 

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THURSDAY, Sept. 23 (HealthDayNews) -- About half the patients with aggressive non-Hodgkin's lymphoma in the United States don't receive the recommended dose and schedule of chemotherapy, which reduces their chances for remission or cure, says a University of Rochester Medical Center study. Researchers reviewed data for 4,552 patients in 567 cancer practices across the United States and found that between 48 percent to 53 percent of patients with non-Hodgkin's lymphoma (NHL) were given less than 85 percent of the recommended chemotherapy dose intensity.

THURSDAY, Sept. 23 (HealthDayNews) -- Excessive drinking took more than 75,000 lives in the United States in 2001, shortening the lives of each of those who died by an average of more than 30 years, a new government report says. In all, a total of 2.3 million "years of potential life" were lost to alcohol abuse, according to the report from the U.S. Centers for Disease Control and Prevention.

FRIDAY, Sept. 24 (HealthDayNews) -- The use of gene therapy to deliver nerve growth factor into areas of the brain where neurons are degenerating, to reverse the ravages of Alzheimer's disease, is being investigated by Rush University Medical Center scientists. If this technique proves successful, it could be a major step forward in finding a way to slow the course of Alzheimer's disease.

Repligen Corp., a biotechnology company that concentrates on pediatric diseases, said Friday that it launched an early-stage clinical trial of a treatment for patients with obsessive-compulsive disorder. Shares of Repligen were up 14 cents, or 7.25 percent, at $2.07 in afternoon trading on the Nasdaq. The Phase I trial of RG1068, a synthetic form of the human hormone secretin, will primarily test the safety and tolerability of two dose levels in up to 16 patients.

 

Anxiety Overview Provided by A.D.A.M., Inc. Definition Anxiety is a feeling of apprehension or fear that lingers. The source for this uneasiness is not always known or recognized which adds to the distress: "Everything stresses me out." "I am always worried." Alternative Names Feeling uptight; Stress; Tension; Jitteriness; Apprehension

 

 

 


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