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Mesothelioma: A Killer Lurks in the Lungs

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The poison in smoke

Smokers exhale high levels of a poison linked to asthma and bronchitis that can seriously affect the breathing of those around them, research by a team of scientists in Sweden has found. 

For the first time scientists have shown that endotoxins, that are made by bacteria and occur naturally in the air, are produced by tobacco smoke in high concentrations. 

The findings will add weight to growing calls for a ban on smoking in enclosed public areas such as pubs, restaurants and other workplaces. 

The researchers from Lund University in Sweden used a unique method of chemical analysis to measure levels of endotoxins caused by tobacco smoke. 

Tobacco is known to contain more than 4,000 chemicals, including 50 substances that have been shown to cause cancer. In high concentrations, endotoxins can cause serious inflammatory reactions in the respiratory tract, leading to bronchitis and asthma. But it has not been clearly shown before that cigarette smoke contains true endotoxins, bacterial lipopolysaccharides. 

The Swedish team, led by Associate Professor Lennart Larsson, found that the level of the toxic substances in the air of a smoky room was 120 times higher than in a smoke-free room. 

The team also concluded that the tobacco endotoxin appeared to be the most aggressive type among the various forms that exist. “This can be one reason why smokers so often suffer from respiratory ailments,” Professor Larsson said. – dpa  

Regenerating hearts 

Infusing patients with bone marrow cells can reinvigorate their dying hearts and grow tiny new arteries and heart muscle tissue, a treatment that may one day make many heart transplants unnecessary, Brazilian researchers said. Dr Hans Fernando Dohmann, coordinator of the research carried out at the Pro-Cardiac Hospital in Rio de Janeiro, said four patients out of the five studied no longer needed transplants after being treated with stem cells. – Reuters 

Suicide risk 

Babies of teenage mothers and infants who have a low birth weight have a higher risk of committing suicide later in life than other children, Swedish scientists said.  

In a study of more than 700,000 young adults, researchers at the Karolinska Institute in Stockholm found that infants born to young mothers or those who weighed 2kg at birth were twice as likely to try to kill themselves. – Reuters 

No link 

Infection with simian virus 40 (SV40) plays little or no role in the development of mesothelioma, a cancer affecting the lining of the lungs that has been linked to asbestos exposure, according to a report in The Lancet.  

In the 1950s and 1960s, several hundred thousand military recruits in the United States received a vaccine contaminated with SV40. Since then, concerns have been raised that SV40 may cause cancer after researchers noticed the presence of its DNA in various tumour specimens. – Reuters 

No racial factor  

There is no difference in survival between black and white patients with heart disease who undergo angioplasty, a procedure to open blocked heart blood vessels, new research shows. Cardiologists from Beth Israel Medical Centre in New York analysed the impact of race on 3,783 patients who underwent angioplasty between 1998 and 1999. The group included 462 black and 3,321 white patients. – Reuters

 

 

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Health group plays down asbestos fears Wednesday, 29 September 2004 Echuca Regional Health has moved to put to rest concerns about staff and the public being exposed to asbestos. The Health Services Union is worried about health risks from demolition works planned for new theatres at the hospital.

EU Approvals: Eloxatin, Raptiva, Alimta, Xenical Yael Waknine Sept. 28, 2004 — The European Commission has approved the following drugs for use in the European Union: oxaliplatin in the adjuvant treatment of stage III colon cancer, efalizumab for moderate to severe chronic plaque psoriasis, pemetrexed in combination with cisplatin for malignant pleural mesothelioma, and pemetrexed monotherapy as second-line therapy for non-small cell lung cancer. In addition, the 2.5-kg pretreatment weight loss requirement has been removed from the label for orlistat.

Asbestos-related shares fall on dim fund prospects Tue Sep 28, 2004 01:37 PM ET NEW YORK, Sept 28 (Reuters) - Shares of companies facing asbestos claims fell Tuesday after prospects dimmed for establishing a victims' compensation fund this year.

Asbestos demand delivered Melinda Browning Wednesday, 29 September 2004 ECHUCA Regional Health has been given an ultimatum to prove the hospital is asbestos-free by today. The Health Services Union has demanded to see documentation of the hospital's asbestos elimination procedure within 24 hours, following a meeting between the parties yesterday afternoon.

Chair of the Ra'anana Committee for the Environment Vered Molko recently convened a meeting of the city engineer, the head of the engineering department, and the chairman of the city Planning and Building Committee to discuss the matter of asbestos in buildings, reports Al Hasharon.


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